Foundations of comparative genomics / Arcady R. Mushegian.
By: Mushegian, Arcady R.
Publisher: Amsterdam ; Boston : Academic Press, c2007Description: ix, 265 p. : ill. ; 27 cm.ISBN: 9780120887941 (hard cover : alk. paper); 0120887940 (hard cover : alk. paper).Subject(s): Genomics | Gene mapping | Physiology, Comparative | Genomics -- methods | Genetic Techniques | Sequence Analysis -- methodsOnline resources: Full-text hereItem type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Book | Skoltech library Shelves | QH447 .M88 2007 (Browse shelf) | Available | 2000006207 |
Includes bibliographical references (p. 238-257) and index.
The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology.
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